1932 – Born on April 26th in Blackpool, England. A British-born Canadian biochemist who developed the technique called oligonucleotide-based site-directed mutagenesis, which enabled researchers to introduce specific mutations into genes and, thus, to the proteins that they encode.
1956 – Smith received a Ph.D. from the University of Manchester, England.
– He moved to Vancouver, Canada.
1964 – Became a Canadian citizen.
1966 – After holding a number of positions in Canada and the United States, he joined the faculty of the University of British Columbia.
1987 – Become the director of the university’s biotechnology laboratory.
– He was a founder of ZymoGenetics Inc., a biotechnology company.
1993 – He won (with Kary B. Mullis) the Nobel Prize for Chemistry.
2000 – He died on October 4th in Vancouver, British Columbia, Canada.