Heraclitus

535 - Heraclitus was born.

- Diogenes also tells us that he deposited his book as a dedication in the great temple of Artemis, the Artemesium, one of the largest temples of the 6th century BCE.

- He disagreed with Thales, Anaximander, and Pythagoras about the nature of the ultimate substance, and instead claimed that the nature of everything is change itself.

475 - his eventual death from illness, including his supposed attempt to stave off death using dung and ignoring doctors.