1416 – He was born this year in Borgo San Sepolcro.
1439 – He was working with Domenici Veneziano on frescoes for the hospital of Santa Maria Nuova in Florence. He also worked in Rimini, Ferrara, and Rome.
1460 – He painted The Flagellation which is one of the most famous and controversial pictures of Renaissance.
1466 – The unfinished facade of the church of San Francesco in the Tuscan city of Arezzo is home to what is generally considered one of his masterpiece in early Renaissance painting, a cycle of frescoes depicting the Legend of the True Cross.
1492 – He died this year in Borgo San Sepolcro.