Died: 1504 AD
queen of Castile 1474-1504
queen of Spain 1479-1504 (co-regent with Ferdinand II 1479-1504
1st queen of united Spain)
supplied aid to Christopher Columbus
wife of Ferdinand II 1469
1st historical woman depicted on US postage stamp 1893
and the great,great,great,great,about 4 more greats of a grandmother to isabelle.