1799 - Born on the 8th of March in Maytown, Lancaster County, Pennsylvania.
1816 - Apprenticed to Andrew Kennedy, Editor of "Northumberland County Gazette" Newspaper.
1821 - Editor of the "Bucks County Messenger" Newspaper, of Doylestown, Pa.
1821 - Partnered with Publisher of "Doylestown Democrat" and merged both Newspapers to form "Bucks County Democrat."
1822 - Moved to Washington, D.C., and studied political movements while journeyman printer for the printing firm of Gales and Seaton.
1822-1829 - Served as State Printer of Pennsylvania.
1823 - Returned to Harrisburg, Pennsylvania as Managing Partner of "Pennsylvania Intelligencer" Newspaper.
1824 - Purchased and ran Newspaper, "The Republican."
1826 - Began building one or two sections of Canal between Sunbury and Harrisburg, Pa.
1826 - Became the State Adjutant General.
1831 - Awarded contract for Canal to be built from New Orleans to Lake Pontchartrain, Louisiana.
1832 - Founded the Bank of Middletown and engaged in other business enterprises.
1838 - Appointed as Commissioner to settle claims of the Winnebago Indians.
1844 - Elected to the Senate to replace James Buchanan.
1860 - Nominated Pennsylvania candidate for President by newly formed Republican Party.
1861 - Appointed Secretary of War by Abraham Lincoln.
1862 - Resigned early to distance Mr. Lincoln from allegations of scandal and was succeeded by Edwin M. Stanton.
1862 - Appointed Minister or Ambassador to Russia by Abraham Lincoln.
1866-1877 - Cameron was again elected to the Senate.
1876 - He resigned and was replace by his son James Donald Cameron.
1889 - Retired to his farm at Donegal Springs near Maytown, Pennsylvania where he died on 26th of June at 90 years of age.
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- "An honest politician is one who, when he is bought, will stay bought."