1770 – She was born at Fort Niagara, was the daughter of a surgeon in the Royal American Regiment and Isabella Graham, a pioneer in humanitarian work.
1789 – She spent her early years in Antigua and Scotland, returning to America.
– She joined her mother teaching school and working in New York City charities.
1802 – Seven years after their marriage, the Bethunes founded the first Sunday school in New York City; they remained active in the movement throughout their lives.
1806 – She was instrumental in founding the New York Orphan Asylum.
1860 – She died in New York City.