1966 – Alexie was born in Spokane, Washington on the 7th of October.
1969 – He was able to read at the age of three.
1971 – When he reached the age of five, he was already reading novels.
1985 – Attended and graduated from Reardan High. Entered Gonzaga University thru scholarship. Attended Gonzaga University for two years and transferred to Washington State University in Pullman, Washington.
1991 – Graduated with a degree in American Studies and he received the Washington State Arts Commission Poetry Fellowship.
1992 – Received the National Endowment for the Arts Poetry Fellowship. His poetry collections entitled The Business of Fancydancing and I Would Steal Horses was published.
1993 – Atlantic Monthly Press published his first complete collection of short stories entitled The Lone Ranger and Tonto Fistfight in Heaven. The collection earned him a PEN/Hemingway Award for Best First Book of Fiction and a Lila Wallace-Reader’s Digest Writers’ Award.
1995 – Published his first novel entitled Reservation Blues in which he was branded one of Granta’s Best of Young American Novelists. He won two awards namely, Before Columbus Foundation’s American Book Award and Murray Morgan Prize.
1998 – Won his first World Heavyweight Poetry Bout June of 1998 after beating the world champion Jimmy Santiago Baca. He wrote and produced the movie "Smoke Signals".
1999 – Made his debut as a stand-up comedian at Foolproff and he was the featured performer at the Vancouver International Comedy Festival’s opening night gala.
2000-2001 – Became a member of the Independent Spirit Awards Nominating Committees, served as a creative adviser to the Sundance Institute Writers Fellowship Program and the Independent Feature Films West Screenwriters Lab.
2003 – He was invited to the University of Washington’s 2003 commencement ceremony as the commencement speaker and participated in the Museum of Tolerance project, "Finding Our Families, Finding Ourselves." He received the 2003 Regents’ Distinguished Alumnus Award, Washington State University’s highest honor for alumni.
2004-2006 – Became an Artist in Residence at the University of Washington and taught courses in American Ethnic Studies.